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Revvity Health Sciences Inc Revvity Health Sciences Cas9-gRNA Globin Depletion Enzyme, Human, RNA-seq

Catalog No. NC3993770
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This Cas9-gRNA Globin Depletion Enzyme (Human) is a flexible CRISPR-Cas9 module for removing globin-derived sequences from human blood RNA-seq libraries. It integrates into workflows at the double-stranded DNA stage, reducing hemoglobin background to improve transcriptome coverage. It contains 30 guide RNAs targeting HBA1, HBA2, HBB, and HBD loci.

  • Reduces globin-derived reads for improved gene sequencing.
  • Uses DASH-style CRISPR-Cas9 depletion.
  • Pre-complexed Cas9 and guide RNA cleave human globin genes at dsDNA stage.
  • Ready-to-use Cas9-gRNA complex.
  • Fast reaction: one hour with five minutes hands-on time.
  • Compatible with short- and long-read sequencing.
  • Depletes 1–10 ng of target dsDNA (library size greater than or equal to 400 bp).
  • Suitable for degraded or low-input samples.
  • Automation compatible.
  • For research use only.

Catalog No. NC3993770 Supplier Revvity Health Sciences Inc Supplier No. NOVA802100
May include imposed supplier surcharges.
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This Cas9-gRNA Globin Depletion Enzyme (Human) is a flexible CRISPR-Cas9 module for removing globin-derived sequences from human blood RNA-seq libraries. It integrates into workflows at the double-stranded DNA stage, reducing hemoglobin background to improve transcriptome coverage. It contains 30 guide RNAs targeting HBA1, HBA2, HBB, and HBD loci.

  • Reduces globin-derived reads for improved gene sequencing.
  • Uses DASH-style CRISPR-Cas9 depletion.
  • Pre-complexed Cas9 and guide RNA cleave human globin genes at dsDNA stage.
  • Ready-to-use Cas9-gRNA complex.
  • Fast reaction: one hour with five minutes hands-on time.
  • Compatible with short- and long-read sequencing.
  • Depletes 1–10 ng of target dsDNA (library size greater than or equal to 400 bp).
  • Suitable for degraded or low-input samples.
  • Automation compatible.
  • For research use only.

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