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STEMCELL Technologies RG108, Size: 5 mg
Supplier: STEMCELL Technologies 72212
RG108 is an epigenetic modifier that inhibits DNA methyltransferase (IC₅₀ = 115 nM). RG108 is a non-nucleoside inhibitor that acts by direct binding to the methyltransferase enzyme whereby it blocks the enzyme active site. (Brueckner et al., Stresemann et al.) REPROGRAMMING· Enhances reprogramming efficiency of human and mouse somatic cells to induced pluripotent stem (iPS) cells (Mali et al., Pasha et al., Shi et al.).
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