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Medchemexpress LLC Rhamnocitrin | 569-92-6 | MFCD00006839 | 300.26 | 1 MG
SDP

Supplier:  Medchemexpress LLC HYN13531MG

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Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3, and MAPK pathways. It selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons, and is applicable for studying endothelial-related inflammatory diseases and neuroprotection.

  • Scavenges DPPH (IC50=28.38 mM).
  • Up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE).
  • Blocks NFATc3 nuclear translocation and downstream inflammatory factor expression.
  • Induces heme oxygenase HO-1 expression and regulates the ERK/p38 MAPK pathway.
  • Inhibits antioxidant and pro-inflammatory cytokines (e.g., IL-6, IL-8) and adhesion molecules (e.g., ICAM-1, VCAM-1).

Catalog No. 50-004-14705


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