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Medchemexpress LLC Rhapontigenin | 500-65-2 | 20 MG

Supplier: Medchemexpress LLC HYN222920MG
Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal, and antibacterial activities. It is a potent and selective cytochrome P450 1A1 inactivator, demonstrating high selectivity over P450 1A2 and P450 1B1. In vitro, it shows concentration-dependent anti-cancer activity and inhibits TGF-β-mediated epithelial-mesenchymal transition. In vivo, it provides significant protection from pulmonary thrombosis.
- Potent and selective cytochrome P450 1A1 inactivator (IC50 = 400 nM)
- Exhibits anticancer, antioxidant, antifungal, and antibacterial activities
- Inhibits ADP- and collagen-induced platelet aggregation
- Protects against pulmonary thrombosis in mice
- Decreases TGF-β triggered increased snail expression in cancer cells
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