Rhein, 97%

Description

CAS: 478-43-3 | C15H8O6 | 284.223 g/mol

Rhein is used to inhibit growth factor beta-1 induced plasminogen activator inhibitor-1 in endothelial cells. It acts as an antibacterial agent against Staphylococcus aureus. It is also used as a laxative. Further, it is employed as a pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Rhein is used to inhibit growth factor beta-1 induced plasminogen activator inhibitor-1 in endothelial cells. It acts as an antibacterial agent against Staphylococcus aureus. It is also used as a laxative. Further, it is employed as a pharmaceutical intermediate.

Solubility
Soluble in sodium hydroxide. Insoluble in water, dimethylsulfoxide and ethanol.

Notes
Incompatible with oxidizing agents. Heat sensitive.

Specifications

Chemical Identifiers

• CAS: 478-43-3
• Molecular Formula: C15H8O6
• Molecular Weight (g/mol): 284.223
• MDL Number: MFCD00009618
• InChI Key: FCDLCPWAQCPTKC-UHFFFAOYSA-N
• Synonym: rhein, monorhein, rheic acid, rhubarb yellow, cassic acid, chrysazin-3-carboxylic acid, 4,5-dihydroxyanthraquinone-2-carboxylic acid, 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, rheinic acid, 1,8-dihydroxyanthraquinone-3-carboxylic acid
• PubChem CID: 10168
• ChEBI: CHEBI:8825
• IUPAC Name: 4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid
• SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(C=C3C2=O)C(=O)O)O

• Melting Point: >300°C
• Quantity: 250 mg
• Beilstein: 2222155
• Solubility Information: Soluble in sodium hydroxide. Insoluble in water,dimethylsulfoxide and ethanol.
• Formula Weight: 284.22
• Percent Purity: 98%
• Chemical Name or Material: Rhein

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	207-521-4
RTECSNumber	CA9516000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only