Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Rhosin (hydrochloride) | 1281870-42-5 | 99.9% | 394.86 | 25 MG
Supplier: Medchemexpress LLC 25MGHY12646
Rhosin hydrochloride is a potent and specific inhibitor of the RhoA subfamily of Rho GTPases. It specifically binds to RhoA to inhibit RhoA-GEF interaction without interacting with Cdc42, Rac1, or the GEF, LARG. This compound induces cell apoptosis and promotes stress resiliency by enhancing D1-MSN plasticity and reducing hyperexcitability.
- Potent and specific inhibitor of the RhoA subfamily of Rho GTPases.
- Specifically binds to RhoA, inhibiting RhoA-GEF interaction.
- Induces cell apoptosis.
- Promotes stress resiliency.
- Reduces RhoA and p-MLC1 activities.
- Prevents social avoidance and blocks sucrose preference deficits.
- Attenuates stress-induced social avoidance and hyperexcitability.
- Enhances spine density in defeat mice.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?