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Apexbio Technology LLC RIBOCICLIB-D6-1MG
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Catalog No. 5000570416
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Ribociclib-d6 (CAS No 1328934-40-2) is a deuterium-labeled analog of Ribociclib categorized under cyclin-dependent kinase inhibitors used in cancer research It originates from medicinal chemistry focused on enhancing pharmacokinetic properties This compound selectively inhibits CDK4 and CDK6 thereby blocking the phosphorylation of the retinoblastoma protein which leads to cell cycle arrest in the G1 phase In vitro Ribociclib-d6 demonstrates activity in the nanomolar to low micromolar range making it a valuable tool for studying the inhibition of cancer cell proliferation It is commonly used in various experimental frameworks including cell models and animal studies to evaluate its efficacy and mechanism Furthermore it plays a significant role in drug screening processes for developing targeted cancer therapies Experimental concentrations typically depend on the specific research design ensuring adaptability to diverse experimental setups

Catalog No. 50-005-70416 Supplier Apexbio Technology LLC Supplier No. SL10641
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Ribociclib-d6 (CAS No 1328934-40-2) is a deuterium-labeled analog of Ribociclib categorized under cyclin-dependent kinase inhibitors used in cancer research It originates from medicinal chemistry focused on enhancing pharmacokinetic properties This compound selectively inhibits CDK4 and CDK6 thereby blocking the phosphorylation of the retinoblastoma protein which leads to cell cycle arrest in the G1 phase In vitro Ribociclib-d6 demonstrates activity in the nanomolar to low micromolar range making it a valuable tool for studying the inhibition of cancer cell proliferation It is commonly used in various experimental frameworks including cell models and animal studies to evaluate its efficacy and mechanism Furthermore it plays a significant role in drug screening processes for developing targeted cancer therapies Experimental concentrations typically depend on the specific research design ensuring adaptability to diverse experimental setups

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