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TARGETMOL CHEMICALS INC RIDAFOROLIMUS 25MG

Supplier: TARGETMOL CHEMICALS INC T633425MG
Also available in 5 mg 10 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ridaforolimus (AP23573) is a small molecule and non-prodrug analogue of the lipophilic macrolide antibiotic rapamycin with potential antitumor activity. Ridaforolimus binds to and inhibits the mammalian target of rapamycin (mTOR) which may result in cell cycle arrest and consequently the inhibition of tumor cell growth and proliferation. Upregulated in some tumors mTOR is a serine/threonine kinase involved in regulating cellular proliferation motility and survival that is located downstream of the PI3K/Akt signaling pathway. purity: 98%
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