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Rifabutin, 98%, Thermo Scientific™

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Quantity:
1g
5g
72559-06-9
C46H62N4O11
847.02
MFCD00866816
ATEBXHFBFRCZMA-VXTBVIBXSA-N
rifabutin, ansamycin, rifabutine, mycobutin, ansatipine, ansatipin, alfacid, rifabutina, rifabutinum, antibiotic lm 427
57448257
(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1⁴,⁷.0⁵,³¹.0²⁶,³⁰]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC(C)C)CC5)N=C1C4=C3C2=O
72559-06-9
C46H62N4O11
847.02
MFCD00866816
ATEBXHFBFRCZMA-VXTBVIBXSA-N
rifabutin, ansamycin, rifabutine, mycobutin, ansatipine, ansatipin, alfacid, rifabutina, rifabutinum, antibiotic lm 427
57448257
(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1⁴,⁷.0⁵,³¹.0²⁶,³⁰]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC(C)C)CC5)N=C1C4=C3C2=O

Rifabutin, CAS # 72559-06-09, is a broad-spectrum antibiotic with activity against mycobacteria, gram-positive and gram-negative bacteria.

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description
Rifabutin is a compound with antibacterial activity most commonly used against Mycobacterium tuberculosis
Rifabutin is a derivative of Rifamycin S that acts through blocking RNA polymerase subunit beta (RpoB)
Rifabutin is an inducer as well as a substrate of CYP3A, a cytochrome P450 enzyme
Applications
Rifabutin may be used in pharmacokinetic laboratory studies and high-throughput drug screens
May be used in laboratory studies to determine drug resistance mutations present in Mycobacterium tuberculosis strains
Assay Percent Range 97.5% min. (HPLC)
Quantity 5g
Formula Weight 847
Percent Purity 98%
Chemical Name or Material Rifabutin

GHS Signal Word: Warning

RUO – Research Use Only