Cayman Chemical RImntadInhydrochlorIde 100mg

Supplier:  Cayman Chemical 23838100 MG

A derivative of amantadine with antiviral activity; inhibits recombinant influenza A M2 protein expressed in X. laevis oocytes (IC50 = 10.8 µM); inhibits recombinant HCV p7 protein expressed in HEK293 cells (IC50s = 0.7, 24, 1.6, and 3.0 nM for HCV genotypes 1a, 2a, 3a, and 4a, respectively); inhibits cytotoxicity induced by the influenza A strains A/PR/8/34 (H1N1) and A/HK/7/87 (H3N2), but not the influenza B strain B/HK/72, in MDCK cells (EC50s = 18, 0.62, and >500 µM, respectively); increases the survival rate of mice infected with the influenza A strain infected with the influenza A strain A2/Jap/305 from 20 to 90% at 24 mg/kg when administered two hours post-infection; has trypanocidal activity against bloodstream forms of T. brucei in vitro (IC50 = 1.26 UG/ml)

Catalog No. 50-299-4931