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Apexbio Technology LLC Rimonabant 168273-06-1 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B14295.1
Rimonabant (SR141716) is a selective antagonist targeting the cannabinoid type 1 (CB1) receptor It exhibits affinity for CB1 receptors with a Ki of approximately 1 8 nM contrasting with a lower affinity for CB2 receptors (Ki 514 nM) Through blocking CB1 receptor signaling this compound is primarily utilized experimentally to investigate behaviors associated with appetite control energy balance and substance consumption Studies using animal models demonstrate that administration of Rimonabant reduces intake of palatable foods and beverages as well as sucrose and alcohol consumption highlighting its relevance in obesity feeding behavior and addiction-related research contexts
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