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Sigma Aldrich Fine Chemicals Biosciences Rink Amide resin (100-200 mesh), 25G, 183599-10-2, MFCD00240214
Supplier: Sigma Aldrich Fine Chemicals Biosciences 8550010025
An excellent support for the Fmoc SPPS of peptide amides. This resin is more acid sensitive than Rink Amide AM and Rink Amide MBHA resins. Cleavage with high concentrations of TFA can lead to the breakdown of the linker, with the concomitant formation of by-products that can not be removed by simple washes. These problems appear to be minimized through the use of low TFA concentrations or by the addition of trialkylsilanes to the cleavage mixture. Color (visual): white to pale yellow to beige.
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