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Cayman Chemical RIpasudIlhydroCLOrID hydr 10mg
SDP

Catalog No. 502984827
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A ROCK1 and ROCK2 inhibitor (IC50s = 51 and 19 nM, respectively); selective for ROCK1 and ROCK2 over PKACα and PKC (IC50s = 2,100 and >10,000 nM, respectively); reduces intraocular pressure in cynomolgus monkey at 0.4%; increases the outflow facility of the aqueous humor in rabbit eyes at 0.4%; decreases intraocular pressure, retinal ganglion cell death, and thinning of inner retinal layers, as well as improves retinal function, in an EAAT1 knockout mouse model of normal tension glaucoma

Catalog No. 50-298-4827 Supplier Cayman Chemical Supplier No. 1992010 MG
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A ROCK1 and ROCK2 inhibitor (IC50s = 51 and 19 nM, respectively); selective for ROCK1 and ROCK2 over PKACα and PKC (IC50s = 2,100 and >10,000 nM, respectively); reduces intraocular pressure in cynomolgus monkey at 0.4%; increases the outflow facility of the aqueous humor in rabbit eyes at 0.4%; decreases intraocular pressure, retinal ganglion cell death, and thinning of inner retinal layers, as well as improves retinal function, in an EAAT1 knockout mouse model of normal tension glaucoma

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