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Medchemexpress LLC HY-112306 10mg Medchemexpress, Ripretinib CAS:1442472-39-0 Purity:>98%
Supplier: Medchemexpress LLC HY11230610MG
Medchemexpress, HY-112306 10mg Ripretinib CAS:1442472-39-0 Ripretinib (DCC-2618) is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. Ripretinib (DCC-2618) targets and binds to both wild-type and mutant forms of KIT and PDGFRA specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. Ripretinib (DCC-2618) also inhibits multiple other kinase targets, such as FLT3 and KDR (or VEGFR-2)[2]. DCC-2618 exerts antineoplastic effect and induces apoptosis[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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