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Selleck Chemical LLC Ripretinib S8757-25MG
SDP

Supplier:  Selleck Chemical LLC S875725MG

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Ripretinib is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) Kit (c-Kit) and PDGFR-alpha with IC50 values of 4 nM 8 nM 18 nM 5 nM and 14 nM for WT Kit (c-Kit) V654A Kit (c-Kit) T670I Kit (c-Kit) D816H Kit (c-Kit) and D816V Kit (c-Kit) respectively

Catalog No. 50-000-24091


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