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Enzo Life Sciences RITA (5mg). CAS: 213261-59-7
Supplier: Enzo Life Sciences ALX430151M005
Inhibitor of p53/HDM2 interaction. Activator of p53 function in tumors. Potently inhibits the growth of a variety of cancer cell lines in the submicromolar range. It has been suggested that RITA selectively targets cells expressing p53 by other mechanisms than direct binding to the N-terminal domain of p53. Alternative name: Reactivation of p53 and Induction of Tumor Cell Apoptosis, 5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol, NSC652287. Purity: ≥98% (HPLC). Solubility: Soluble in 100% ethanol (1mg/ml), DMSO (20mg/ml), dimethyl formamide (30mg/ml); 0.5mg/ml soluble in a 1:1 solution of dimethyl formamide: PBS (pH 7.2) (dissolve RITA first in dimethyl formamide and then dilute with PBS). Long Term Storage: -20°C.
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