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AdipoGen Ritonavir
Supplier: AdipoGen AGCR13683M050
Chemical. CAS 155213-67-5. Formula C37H48N6O5S2. MW 720.9. . HIV-1 and HIV-2 protease inhibitor. Glucose transporter 1 GLUT1 and 4 GLUT4 inhibitor. Inhibits transport of glucose across the plasma membranes of mammalian cells and consequently decreases glycolysis. Useful agent for immunometabolism research. Antitumor agent. Apoptosis inducer and cell proliferation inhibitor in GLUT1/GLUT4 overexpressed cancer cell lines. Tumor cells rely on elevated glucose consumption and metabolism for survival and proliferation. Glucose transporters mediating glucose entry are key proximal rate-limiting checkpoints. Among the fourteen SLC2A family members, GLUTs 1 and 4 are high-affinity glucose transporters.
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