Cayman Chemical RIvnIclInhydrochlorIde 10mg

Supplier:  Cayman Chemical 4218410 MG

An α4β2 subunit-containing nAChR agonist; selectively induces rubidium ion efflux in M10 cells expressing α4β2 subunit-containing nAChRs (EC50 = 0.73 µM for the chicken channels) over M10 cells expressing α3β4- or α1β1γδ subunit-containing receptors (EC50s = >1,000 nM for both for the chicken channels) and a panel of 34 receptors, ion channels, and kinases at 10 µM; induces contractions in isolated guinea pig ileum (EC30 = 15 µM); prevents scopolamine-induced memory deficits in the passive avoidance test in mice at 0.6 µmol/kg; decreases the number of errors in the radial arm maze in a rat model of ibotenic acid-induced memory impairment at 0.3, 0.6 or 1.2 µmol/kg

Catalog No. 50-294-5868