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Cayman Chemical Rivanicline (hydrochloride), Purity: ≥98%, 5 mg
SDP

Catalog No. 502945869
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An α4β2 subunit-containing nAChR agonist; selectively induces rubidium ion efflux in M10 cells expressing α4β2 subunit-containing nAChRs (EC50 = 0.73 µM for the chicken channels) over M10 cells expressing α3β4- or α1β1γδ subunit-containing receptors (EC50s = >1,000 nM for both for the chicken channels) and a panel of 34 receptors, ion channels, and kinases at 10 µM; induces contractions in isolated guinea pig ileum (EC30 = 15 µM); prevents scopolamine-induced memory deficits in the passive avoidance test in mice at 0.6 µmol/kg; decreases the number of errors in the radial arm maze in a rat model of ibotenic acid-induced memory impairment at 0.3, 0.6 or 1.2 µmol/kg

Catalog No. 50-294-5869 Supplier Cayman Chemical Supplier No. 421845 MG
May include imposed supplier surcharges.
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An α4β2 subunit-containing nAChR agonist; selectively induces rubidium ion efflux in M10 cells expressing α4β2 subunit-containing nAChRs (EC50 = 0.73 µM for the chicken channels) over M10 cells expressing α3β4- or α1β1γδ subunit-containing receptors (EC50s = >1,000 nM for both for the chicken channels) and a panel of 34 receptors, ion channels, and kinases at 10 µM; induces contractions in isolated guinea pig ileum (EC30 = 15 µM); prevents scopolamine-induced memory deficits in the passive avoidance test in mice at 0.6 µmol/kg; decreases the number of errors in the radial arm maze in a rat model of ibotenic acid-induced memory impairment at 0.3, 0.6 or 1.2 µmol/kg

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