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Medchemexpress LLC RKI-1447 dihydrochloride | 1782109-09-4 | 99.9% | 399.29 | 50 MG
SDP

Catalog No. 5000343970
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RKI-1447 dihydrochloride is a potent and selective ROCK inhibitor, effectively targeting ROCK1 and ROCK2. It has been shown to suppress colorectal carcinoma cell growth and promote apoptosis, exhibiting antitumor activity both in vitro and in vivo.

  • Potent and selective ROCK inhibitor (IC50s of 14.5 nM for ROCK1 and 6.2 nM for ROCK2).
  • Suppresses colorectal carcinoma cell growth.
  • Promotes apoptosis.
  • Inhibits phosphorylation of ROCK substrates MLC-2 and MYPT-1 in human cancer cells.
  • Demonstrates antitumor activity in vivo in models of mammary tumor and colorectal carcinoma.

Catalog No. 50-003-43970 Supplier Medchemexpress LLC Supplier No. HY11033950MG
May include imposed supplier surcharges.
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RKI-1447 dihydrochloride is a potent and selective ROCK inhibitor, effectively targeting ROCK1 and ROCK2. It has been shown to suppress colorectal carcinoma cell growth and promote apoptosis, exhibiting antitumor activity both in vitro and in vivo.

  • Potent and selective ROCK inhibitor (IC50s of 14.5 nM for ROCK1 and 6.2 nM for ROCK2).
  • Suppresses colorectal carcinoma cell growth.
  • Promotes apoptosis.
  • Inhibits phosphorylation of ROCK substrates MLC-2 and MYPT-1 in human cancer cells.
  • Demonstrates antitumor activity in vivo in models of mammary tumor and colorectal carcinoma.

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