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ATCC RLE-6TN; Alveolar Epithelium; Rat (Rattus norvegicus)
Supplier: ATCC CRL2300

RLE-6TN is an alveolar cell that was isolated from the lung of a 56-day-old male FISCHER 344 (F344) rat. At passage 5, the alveolar Type II cells were transfected with SV40 (pRSV-T DNA) by lipofection. Expression of the SV40-T antigen was negative by nuclear immunostaining and by PCR, indicating these cells were derived by a spontaneous immortalization. The cell was deposited by KE Driscoll.
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