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Medchemexpress LLC RN-1665 | 1803003-65-7 | 99.9% | 513.54 | 25 MG
Supplier: Medchemexpress LLC 25MGHY160900
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3, and TRPM8. It serves as a TRPV4 probe for focus screens, with IC50 values of 0.26 μM and 0.39 μM for human (hTRPV4) and rat (rTRPV4), respectively.
- Orally active TRPV4 antagonist.
- Shows excellent selectivity for related TRP receptors like TRPV1, TRPV3, and TRPM8.
- Serves as a TRPV4 probe for focus screens.
- IC50 of 0.26 μM for human TRPV4.
- IC50 of 0.39 μM for rat TRPV4.
- Soluble in DMSO (100 mg/mL).
- Powder stable for 3 years at -20°C and 2 years at 4°C.
- In solvent, stable for 6 months at -80°C and 1 month at -20°C.
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