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ABclonal Technology RNF8 Rabbit mAb
Supplier: ABclonal Technology A2252420UL
The protein encoded by this gene contains a RING finger motif and an FHA domain This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2) including UBE2E1 UBCH6 UBE2E2 and UBE2E3 and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest Alternative splicing results in multiple transcript variants
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