Medchemexpress LLC Ro 10-5824 dihydrochloride | 189744-94-3 | 99.9% | 353.29 g/mol | C17H22Cl2N4 | 10 MG

Supplier:  Medchemexpress LLC HY101384A10MG

Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist used in neuroscience and receptor pharmacology research. It binds the D4 receptor with high affinity (Ki ≈ 5.2 nM), shows pronounced selectivity over other dopamine receptor subtypes, and produces partial agonist responses in functional assays; in vivo studies report effects on object recognition and frontal cortex gamma activity without altering spontaneous locomotion.

• High-affinity D4 receptor binding (Ki ≈ 5.2 nM).
• Pronounced selectivity versus other dopamine receptor subtypes.
• Partial agonist activity in functional assays (35S-GTPγS stimulation).
• Demonstrated in vivo activity relevant to cognition and neural oscillations.
• High chemical purity suitable for in vitro and in vivo research.

Catalog No. 50-002-13177