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Apexbio Technology LLC Ro 20-1724 29925-17-5 50mg
Supplier: Apexbio Technology LLC B629450
Ro 20-1724 (CAS 29925-17-5) is a selective inhibitor of phosphodiesterase 4 (PDE4) acting by specifically blocking the degradation of intracellular cyclic adenosine monophosphate (cAMP) This modulation of cAMP-dependent signaling pathways occurs with a reported inhibition constant (Ki) of approximately 1930 nM Recent studies demonstrate that Ro 20-1724 can influence neuronal cell function and exert neuroprotective effects in various cell-based and animal models It is commonly employed to investigate alterations in cellular signaling and pathophysiological mechanisms related to neuronal injury and neurodegenerative disorders
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