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Enzo Life Sciences RO-3306, (1mg), CAS Number: 872573-93-8

Supplier: Enzo Life Sciences ALX270463M001

CDK/cyclin inhibitor. Inhibitor of CDK1/cyclin B1 and CDK1/cyclin A. Reversibly arrests human cells at the G2/M border of the cell cycle. Allows for effective cell synchronisation in early mitosis. Downregulates expression of the antiapoptotic proteins Bcl-2 and survivin and blocks p53-mediated induction of p21 and MDM2. Alternative Name: (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one. Formula: C18H13N3OS2. MW: 351.4. CAS Number: 872573-93-8. Purity: ≥95% (HPLC). Appearance: Brown solid. Solubility: Soluble in DMSO (5mg/ml). Use/Stability: Stable for at least 6 months after receipt when stored at -20°C in the dark. Long Term Storage: -20°C
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