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Enzo Life Sciences Ro 41-5253 (25mg). CAS: 144092-31-9

Supplier: Enzo Life Sciences BMLGR1100025

A selective RARα antagonist (concentration required to inhibit 50% of specific retinoic acid binding: RARα, 60 nM; RARß, 2400 nM; RARτ, 3300 nM). Counteracts the effects of retinoic acid on HL-60 cell differentiation, B-lymphocyte polyclonal activation and in a RARα transactivation assay. Ro 41-5253 suppresses retinoic acid-induced connexin 43 protein expression in 10T1/2 cells. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (50mg/ml) or 100% ethanol (15mg/ml, warm). Long Term Storage: -20°C.
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