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Apexbio Technology LLC Ro 61-8048 199666-03-0 50mg
Supplier: Apexbio Technology LLC B733450
Ro 61-8048 is a small-molecule inhibitor targeting kynurenine 3-hydroxylase (KMO) It is designed to selectively inhibit the catalytic conversion of kynurenine into 3-hydroxykynurenine thereby modulating the kynurenine pathway of tryptophan metabolism Ro 61-8048 exerts its biological activity primarily through selective KMO inhibition In in vitro studies Ro 61-8048 demonstrates inhibitory potency with an IC50 value of approximately 37 nM Based on these pharmacological properties Ro 61-8048 holds research potential in investigations of neurodegenerative and central nervous system immune-related disorders
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