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Abcam Ro 67-4853, Positive allosteric modulator of mGlu1, 50MG
Supplier: Abcam AB12097950MG
MW 325.36 g/mol, Purity >99%. Potent, selective positive allosteric modulator for mGlu₁ (pEC₅₀ = 7.16 for rat mGlu₁a receptors). Increases basal mGluR₁-induced cAMP accumulation and potentiates glutamate-induced cAMP accumulation. Selectively enhanced responses to DHPG in vivo (EC₅₀= 95 nM in CA3 neurons).
The product is subject to the following: Abcam Restricted Use Statement
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