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Cayman Chemical RobenacoxIb 10mg

Supplier: Cayman Chemical 4221810 MG
An NSAID and COX-2 inhibitor (Ki = 30 nM for the human enzyme); selective for COX-2 over COX-1 (Ki = 800 nM for the ovine enzyme); inhibits IL-1β-induced PGE2 production in human dermal fibroblasts (IC50 = 31 nM); reduces carrageenan-induced paw edema (ID50 = 0.4 mg/kg), has antinociceptive activity in the Randall-Selitto test, and inhibits LPS-induced fever in rats
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