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Apexbio Technology LLC Rolapitant HCl 552292-08-7 (free base) 1mg
Supplier: Apexbio Technology LLC B59101
Rolapitant HCl is a small-molecule antagonist targeting the neurokinin NK1 receptor It is designed to block NK1 receptor signaling pathways thereby reducing receptor activation mediated by substance P Rolapitant HCl exerts its biological activity primarily through competitive antagonism of the NK1 receptor In preclinical models including gerbils and ferrets rolapitant suppressed both acute and delayed emetic responses induced by NK1 receptor agonists Based on these pharmacological properties rolapitant HCl holds research potential in the management of postoperative nausea and vomiting
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