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Cayman Chemical Rolpram 10mg
Supplier: Cayman Chemical 3111110 MG
A PDE4 inhibitor (IC50 = 0.22 µM for the guinea pig eosinophil enzyme); enhances isoprenaline-induced cAMP accumulation in isolated guinea pig eosinophils (EC50 = 0.19 µM); inhibits TNF and INF-γ production in L1402 CD4+ encephalitogenic rat T cells from 1-1,000 µM; inhibits ovalbumin-induced contraction of tracheal rings isolated from ovalbumin-sensitized guinea pigs at 1 µM; inhibits ovalbumin-induced bronchoconstriction in guinea pigs (ED50 = 0.25 mg/kg)
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