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Active Motif Romidepsin
Supplier: Active Motif 14083
Active Motif's Romidepsin is a potent and selective inhibitor of class I histone deacetylases (HDACs), IC50 = 36, 47, 510 and 14,000 nM for HDAC1, 2, 4 and HDAC6, respectively. It induces apoptosis in a variety of cell lines and displays anti-tumor activity in mouse models. Romidepsin was recently approved for clinical uses in T-cell lymphoma.
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