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Medchemexpress LLC Ropinirole hydrochloride | 91374-20-8 | 99.9% | 50 MG
Supplier: Medchemexpress LLC HYB0623A50MG
Ropinirole hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for the D2 receptor. It exhibits pEC50s of 7.4, 8.4, and 6.8 for hD2, hD3, and hD4 receptors, respectively, and demonstrates no affinity for D1 receptors. This compound is under investigation for its therapeutic potential in treating Parkinson's disease.
- Potent D3/D2 receptor agonist
- Ki of 29 nM for D2 receptor
- pEC50s of 7.4 (hD2), 8.4 (hD3), and 6.8 (hD4)
- No affinity for D1 receptors
- Higher affinity for D3 receptors compared to D2 and D4 receptors
- Weakly active at alpha 2-adrenoceptors and 5-HT2 receptors
- Inactive at 5-HT1, benzodiazepine, gamma-aminobutyric acid receptors, or alpha 1 and beta-adrenoceptors
- Investigated for potential in treating Parkinson's disease
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