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Medchemexpress LLC Ropivacaine mesylate | 854056-07-8 | 99.5% | 5 MG
Supplier: Medchemexpress LLC HYB0563C5MG
Ropivacaine mesylate is a long-acting amide local anaesthetic agent primarily used for spinal blocks and effective in blocking neuropathic pain. It functions by reversibly inhibiting sodium ion influx in nerve fibers, thereby blocking impulse conduction. This compound also acts as an inhibitor of the K2P (two-pore domain potassium channel) TREK-1, with an IC50 of 402.7 μM in COS-7 cell membranes.
- Functions as a long-acting amide local anaesthetic agent
- Effective for spinal blocks
- Blocks neuropathic pain
- Reversibly inhibits sodium ion influx in nerve fibers
- Inhibits K2P TREK-1 potassium channels (IC50: 402.7 μM)
- Prevents pressure-induced lung edema and hyperpermeability
- Inhibits pressure-induced nitric oxide production
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