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Apexbio Technology LLC Rose Bengal 632-69-9 25g
Supplier: Apexbio Technology LLC B776725000
Rose Bengal (CAS 632-69-9) is a small-molecule inhibitor targeting vesicular glutamate transporter (VGlut) and vesicular monoamine transporter (VMAT) It is designed to inhibit the uptake and storage of glutamate into synaptic vesicles thereby modulating neurotransmitter storage and release Rose Bengal exerts its biological activity primarily through inhibition of glutamate uptake into vesicles without affecting H -ATPase pump activity In vitro experiments demonstrate inhibitory activity with reported Ki values of approximately 19 nM for VGlut and 64 nM for VMAT in isolated synaptic terminals Based on these pharmacological properties Rose Bengal holds research potential in neurobiochemical studies exploring neurotransmitter release and synaptic vesicle trafficking
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