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Medchemexpress LLC Roxithromycin | 80214-83-1 | 5 G
Supplier: Medchemexpress LLC HYB04355G
Roxithromycin is an orally active semi-synthetic macrolide antibiotic that inhibits protein biosynthesis by binding to the 50S bacterial ribosome during the elongation step. It demonstrates antimicrobial, antiproliferative, anti-inflammatory, and tumor vasculature inhibiting effects, also ameliorating lung injury.
- Orally active semi-synthetic macrolide antibiotic
- Inhibits protein biosynthesis in bacterial ribosomes
- Effective against Gram-positive and Gram-negative bacteria
- Exhibits antiproliferative and anti-inflammatory effects
- Inhibits endothelial cell migration and tube formation
- Reduces UV B irradiation-induced reactive oxygen intermediates
- Induces apoptosis to eliminate senescent cells
- Attenuates bleomycin-induced lung injury and fibrosis
- Inhibits constitutive activation of NF-κB and attenuates airway inflammation
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