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Cayman Chemical Rp2DeoxyadenosIn5O 1 2.1mg

Supplier: Cayman Chemical 384532.1 MG

An ETA receptor antagonist (Ki 13 nM in rat aortic vascular smooth muscle cells) inhibits ET-1-induced contractions in isolated rat aortic rings and mesenteric microvessels (pA2s 8.1 and 7.97 respectively) decreases systolic blood pressure in DOCA-salt hypertensive rats at 50 mg/kg decreases MAP and LVDP in normotensive pigs at 1 and 5 mg/kg reduces myocardial infarct size as a percentage of the area at risk in a porcine model of LAD coronary artery ligation-induced ischemia-reperfusion injury
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