Invitrogen™ Human RPS6KA6 (RSK4), GST Tag Recombinant Protein

Catalog No.	Quantity
PV4557	10 μg

Catalog No. PV4557 Supplier Invitrogen™ Supplier No. PV4557

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

RPS6KA6 (RSK4) is a member of the RSK kinases family. RSK family members are activated by ERKs and mitogens and are unusual in that they contain 2 non-identical kinase domains. RSK4 encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways.

Specifications

• Accession Number: Q9UK32
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 27330
• Molecular Weight (g/mol): 111.3 kDa
• Name: Human RPS6KA6 (RSK4), GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 2610524K04Rik; 90 kDa ribosomal protein S6 kinase 6; p90-RSK 6; p90RSK6; pp90RSK4; RGD1560817; ribosomal protein S6 kinase A6; ribosomal protein S6 kinase alpha-6; ribosomal protein S6 kinase polypeptide 6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; ribosomal S6 kinase 4; Rps6ka6; RSK4; RSK-4; S6KA6; S6K-alpha 6; S6K-alpha-6
• Common Name: RSK4
• Gene Symbol: Rps6ka6
• Kinase Family: RSK (RPS6K) Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
  Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Assay Entry: Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
• Mass: 10 μg
• Kinase Group: Ser⁄Thr Kinases: ACG Group
• Shipping Condition: Dry Ice
• System Compatibility: Zin-LYTE™, Omnia™ Bulk Substrate
• Tag Position: N-Terminal
• Target Entry: RPS6KA6
• Target Gene: ribosomal protein S6 kinase, 90kDa, polypeptide 6
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Drug Discovery: Signal Transduction
• Purity or Quality Grade: 90% by SDS-PAGE