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Medchemexpress LLC RS-25344 hydrochloride | 152815-28-6 | 99.9% | 411.80 | 25 MG
Supplier: Medchemexpress LLC 25MGHY108621
RS-25344 hydrochloride is a selective cAMP-phosphodiesterase 4 (PDE 4; PDE IV) inhibitor with an IC50 of 0.28 nM in human lymphocytes. It has only weak inhibitory effects on PDE I, II, and III (IC50 of >100 μM, 160 μM, and 330 μM, respectively). It exhibits anti-inflammatory, memory- and cognition-enhancing, and antineoplastic effects. It is a potent inhibitor of sperm PDE activity, with an effective concentration of 0.3 nM, reaching maximum inhibition in the range of 100 nM. In vivo studies have shown that it can significantly increase stomach weights and gastric retention in mice.
- Selective cAMP-phosphodiesterase 4 (PDE 4; PDE IV) inhibitor.
- Exhibits anti-inflammatory effects.
- Enhances memory and cognition.
- Possesses antineoplastic effects.
- Potent inhibitor of sperm PDE activity.
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