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Apexbio Technology LLC (R,S)-Atenolol,5g CAS# 29122-68-7

Supplier: Apexbio Technology LLC C52865000
(R,S)-Atenolol is a β1-adrenergic receptor antagonist. Beta-adrenoceptor antagonists are widely used in cardiovascular medicine as well as in the management of anxiety, migraine and glaucoma. The mode of action in cardiovascular disease is from antagonism of endogenous catecholamine responses in the heart.In vitro: (R,S)-Atenolol was found to differ slightly regarding potency and to be practically equal regarding relative selectivity, while ICI 141,292 had slightly higher relative selectivity and much higher potency. (R,S)-Atenolol exhibited highest affinity for the beta 1-receptor population. In contrast, ICI 118,551 exhibited a very high relative selectivity with highest affinity for the beta 2-receptor subtype [1]. Other sizes are also available. Please inqury us for quote.
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