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Medchemexpress LLC RS102895 hydrochloride | 1173022-16-6 | 99.9% | 426.86 | 50 MG
SDP

Catalog No. 5000387782
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Abaucin hydrochloride (RS102895 hydrochloride) is a potent CCR2 antagonist (IC50 = 360 nM) that also inhibits human α1a and α1d receptors, and the rat brain cortex 5HT1a receptor. It ameliorates extracellular matrix (ECM) protein expression and blocks fibronectin and type IV collagen expression in high glucose-stimulated mesangial cells.

  • Potent CCR2 antagonist.
  • Inhibits human α1a and α1d receptors.
  • Suppresses MCP-1 receptor activity.
  • Ameliorates extracellular matrix protein expression.
  • Blocks fibronectin and type IV collagen expression.
  • Reverses NR2B, nNOS, and SIGIRR expression in spinal cord.

Catalog No. 50-003-87782 Supplier Medchemexpress LLC Supplier No. HY1861150MG
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Abaucin hydrochloride (RS102895 hydrochloride) is a potent CCR2 antagonist (IC50 = 360 nM) that also inhibits human α1a and α1d receptors, and the rat brain cortex 5HT1a receptor. It ameliorates extracellular matrix (ECM) protein expression and blocks fibronectin and type IV collagen expression in high glucose-stimulated mesangial cells.

  • Potent CCR2 antagonist.
  • Inhibits human α1a and α1d receptors.
  • Suppresses MCP-1 receptor activity.
  • Ameliorates extracellular matrix protein expression.
  • Blocks fibronectin and type IV collagen expression.
  • Reverses NR2B, nNOS, and SIGIRR expression in spinal cord.

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