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Medchemexpress LLC RTI-13951-33 hydrochloride | 98.06% | 532.50 | 1 ML
Supplier: Medchemexpress LLC HY112612A10MM/1ML
RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist. It has an EC50 of 25 nM in GPR88 cAMP functional assay and reduces alcohol reinforcement and intake behaviors in rats. This compound elevates [35S]-GTPγS binding in mouse striatal membranes and demonstrates sufficient brain penetration.
- Potent and selective GPR88 agonist
- Brain-penetrant properties
- Reduces alcohol reinforcement and intake behaviors
- Elevates GTPγS binding in mouse striatal membranes
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