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Medchemexpress LLC RU.521 | 1MG
Supplier: Medchemexpress LLC HY1141801MG
RU 521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation RU 521 suppresses dsDNA-activated reporter activity with an IC50 of 0 7 M RU 521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Gouti res syndrome (AGS)[1]
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