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Medchemexpress LLC HY-114180 5mg Medchemexpress, RU.521 CAS:2262452-06-0 Purity:>98%

Supplier: Medchemexpress LLC HY1141805MG

Medchemexpress, HY-114180 5mg RU.521 CAS:2262452-06-0 RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC 50 of 700 nM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS) [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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