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Medchemexpress LLC RU-SKI 43 hydrochloride | 1782573-67-4 | 98.81% | 423.01 | 1 ML
Supplier: Medchemexpress LLC HY18366A10MM/1ML
RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. This compound exhibits anti-cancer activity and is for research use only.
- Potent and selective Hhat inhibitor
- Reduces Gli-1 activation through Smoothened-independent non-canonical signaling
- Decreases Akt and mTOR pathway activity
- Exhibits anti-cancer activity
- Purity of 98.81%
- Available in solid form
- Soluble in DMSO (≥ 51 mg/mL) and H2O (2.5 mg/mL)
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