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TARGETMOL CHEMICALS INC Ruboxistaurin hydrochloride

Supplier: TARGETMOL CHEMICALS INC T36895MG
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCbetaI and PKCbetaII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCbeta over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 uM for PKCη, -delta, -gamma, -alpha, - and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src). Purity 98.44%
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