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Cayman Chemical RupatdInfumarate 100mg
SDP

Supplier:  Cayman Chemical 29478100 MG

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A histamine H1 and PAF receptor antagonist; binds to rabbit platelet membranes and guinea pig cerebellum membranes (apparent Kis = 0.55 and 0.1 µM, respectively, in radioligand binding assays); inhibits histamine-induced contraction of isolated guinea pig ileum (pA2 = 9.29) and PAF-induced platelet aggregation in washed rabbit platelets (pA2 = 6.68); prevents histamine- or PAF-induced hypotension in rats (ID50s = 1.4 and 0.44 mg/kg, respectively); reverses histamine- or PAF-induced bronchoconstriction in guinea pigs (ID50s = 113 and 9.6 mg/kg, respectively)

Catalog No. 50-298-9856


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