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Cayman Chemical RXR RetInoId X receptr100uL
Supplier: Cayman Chemical 32827100 UL
An inhibitor of PI3K and PI3KY (IC50s 24.5 and 33.2 nM respectively) greater than 300- and 120-fold selective for PI3K and PI3KY respectively over PI3Ka and PI3KB induces cell death in L-540 KM-H2 and L-428 cells at 10 UM induces cell cycle arrest at the G0/G1 phase in the same cells reduces tumor growth and vasculature induces tumor necrosis and induces the M1 phenotype in TAMs in an L-540 mouse xenograft model
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