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Medchemexpress LLC (S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5-methyl-1H-pyrazol-3-ylamino)nicotinonitrile | 905586-69-8 | MFCD16621127 | >98.0% | 354.36 g/mol | C18H16F2N6 | 100 MG
SDP

Catalog No. 5000243431
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AZ960 is a small-molecule, ATP-competitive inhibitor of Janus kinase 2 (JAK2) used as a research reagent to study JAK/STAT signaling and JAK2-driven cellular models. It has high potency and has been used in preclinical studies to induce growth arrest and apoptosis in JAK2-dependent cells.

  • Potent JAK2 inhibition (Ki ≈ 0.45 nM).
  • Selective profile with reduced activity against JAK1, JAK3, and TYK2.
  • High purity (>98% by HPLC) suitable for biochemical and cellular assays.
  • Chemical formula C18H16F2N6 and molecular weight 354.36 g/mol.
  • Solid powder form, soluble in DMSO for stock solutions.
  • Used for JAK/STAT pathway studies and preclinical cell-based assays.

Catalog No. 50-002-43431 Supplier Medchemexpress LLC Supplier No. HY10411100MG
May include imposed supplier surcharges.
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AZ960 is a small-molecule, ATP-competitive inhibitor of Janus kinase 2 (JAK2) used as a research reagent to study JAK/STAT signaling and JAK2-driven cellular models. It has high potency and has been used in preclinical studies to induce growth arrest and apoptosis in JAK2-dependent cells.

  • Potent JAK2 inhibition (Ki ≈ 0.45 nM).
  • Selective profile with reduced activity against JAK1, JAK3, and TYK2.
  • High purity (>98% by HPLC) suitable for biochemical and cellular assays.
  • Chemical formula C18H16F2N6 and molecular weight 354.36 g/mol.
  • Solid powder form, soluble in DMSO for stock solutions.
  • Used for JAK/STAT pathway studies and preclinical cell-based assays.

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